{"id":8065,"date":"2024-12-21T09:58:41","date_gmt":"2024-12-21T06:28:41","guid":{"rendered":"https:\/\/drboroumandp7.com\/fda-approves-first-mesenchymal-stromal-cell-therapy\/"},"modified":"2024-12-21T10:15:36","modified_gmt":"2024-12-21T06:45:36","slug":"fda-approves-first-mesenchymal-stromal-cell-therapy","status":"publish","type":"post","link":"https:\/\/drboroumandp7.com\/en\/fda-approves-first-mesenchymal-stromal-cell-therapy\/","title":{"rendered":"FDA Approves First Mesenchymal Stromal Cell Therapy &#8230;"},"content":{"rendered":"\n<h1 class=\"wp-block-heading has-text-align-left\">FDA Approves First Mesenchymal Stromal Cell Therapy to Treat Steroid-refractory Acute Graft-versus-host Disease<\/h1>\n\n<h2 class=\"wp-block-heading has-text-align-left\">The FDA has approved Ryoncil (remestemcel-L), the first mesenchymal stromal cell (MSC) therapy for treating steroid-refractory acute graft-versus-host disease (SR-aGVHD) in pediatric patients aged two months and older. This approval, announced on December 18, 2024, marks a significant milestone in cell-based therapies for severe conditions like GVHD, which can have devastating effects on patients, particularly children[1][2][4]. Ryoncil is derived from healthy donor bone marrow and has demonstrated a 70% overall response rate in clinical trials[3][5].<\/h2>\n\n<h3 class=\"wp-block-heading has-text-align-left\">Citations:<\/h3>\n\n<p class=\"has-text-align-left has-text-color has-link-color wp-elements-98bf59f275110d4fee3bd0dd4602eabc\" style=\"color:#390e61\">[1] <a href=\"https:\/\/www.biopharma-reporter.com\/Article\/2024\/12\/19\/fda-approves-first-mesenchymal-stromal-cell-therapy\/\">https:\/\/www.biopharma-reporter.com\/Article\/2024\/12\/19\/fda-approves-first-mesenchymal-stromal-cell-therapy\/<\/a><br\/>[2]<a href=\"https:\/\/www.globenewswire.com\/news-release\/2024\/12\/19\/2999457\/0\/en\/mesoblast-s-ryoncil-is-the-first-u-s-fda-approved-mesenchymal-stromal-cell-msc-therapy.html%0A\"> \nhttps:\/\/www.globenewswire.com\/news-release\/2024\/12\/19\/2999457\/0\/en\/mesoblast-s-ryoncil-is-the-first-u-s-fda-approved-mesenchymal-stromal-cell-msc-therapy.html<br\/><\/a>[3] <a href=\"https:\/\/www.cgtlive.com\/view\/fda-approves-mesoblast-remestemcel-steroid-refractory-gvhd\">https:\/\/www.cgtlive.com\/view\/fda-approves-mesoblast-remestemcel-steroid-refractory-gvhd<\/a><br\/>[4] <a href=\"https:\/\/www.biospace.com\/fda\/mesoblast-wins-first-mesenchymal-stromal-cell-therapy-fda-approval-for-gvhd\">https:\/\/www.biospace.com\/fda\/mesoblast-wins-first-mesenchymal-stromal-cell-therapy-fda-approval-for-gvhd<\/a><br\/>[5] <a href=\"https:\/\/www.fda.gov\/drugs\/resources-information-approved-drugs\/fda-approves-remestemcel-l-rknd-steroid-refractory-acute-graft-versus-host-disease-pediatric\">https:\/\/www.fda.gov\/drugs\/resources-information-approved-drugs\/fda-approves-remestemcel-l-rknd-steroid-refractory-acute-graft-versus-host-disease-pediatric<\/a><br\/>[6] <a href=\"https:\/\/www.oncnursingnews.com\/view\/fda-approves-first-msc-therapy-in-steroid-refractory-gvhd\">https:\/\/www.oncnursingnews.com\/view\/fda-approves-first-msc-therapy-in-steroid-refractory-gvhd<\/a><br\/>[7] <a href=\"https:\/\/www.fiercepharma.com\/pharma\/fda-nod-gvhd-cell-therapy-gives-australian-biotech-mesoblast\">https:\/\/www.fiercepharma.com\/pharma\/fda-nod-gvhd-cell-therapy-gives-australian-biotech-mesoblast<\/a><br\/>[8] <a href=\"https:\/\/www.medscape.com\/viewarticle\/fda-oks-first-mesenchymal-stromal-cell-therapy-gvhd-2024a1000onu\">https:\/\/www.medscape.com\/viewarticle\/fda-oks-first-mesenchymal-stromal-cell-therapy-gvhd-2024a1000onu<\/a><br\/>[9] <a href=\"https:\/\/www.reuters.com\/business\/healthcare-pharmaceuticals\/us-fda-approves-mesoblasts-cell-therapy-graft-versus-host-disease-2024-12-18\/\">https:\/\/www.reuters.com\/business\/healthcare-pharmaceuticals\/us-fda-approves-mesoblasts-cell-therapy-graft-versus-host-disease-2024-12-18\/<\/a><br\/>[10] <a href=\"https:\/\/www.nature.com\/articles\/s41423-023-01022-z\">https:\/\/www.nature.com\/articles\/s41423-023-01022-z<\/a><br\/><a href=\"https:\/\/www.globenewswire.com\/news-release\/2024\/11\/07\/2976830\/28124\/en\/Graft-Versus-Host-Disease-GvHD-Treatment-Industry-Forecast-Report-2024-2032-Global-Market-Size-Forecast-to-Double-with-Emerging-Markets-Offering-Substantial-Growth-Potential.html%0A\">https:\/\/www.globenewswire.com\/news-release\/2024\/11\/07\/2976830\/28124\/en\/Graft-Versus-Host-Disease-GvHD-Treatment-Industry-Forecast-Report-2024-2032- Global-Market-Size-Forecast-to-Double-with-Emerging-Markets-Offering-Substantial-Growth-Potential.html<br\/><\/a>[12] <a href=\"https:\/\/www.fda.gov\/news-events\/press-announcements\/fda-approves-first-mesenchymal-stromal-cell-therapy-treat-steroid-refractory-acute-graft-versus-host\">https:\/\/www.fda.gov\/news-events\/press-announcements\/fda-approves-first-mesenchymal-stromal-cell-therapy-treat-steroid-refractory-acute-graft-versus-host<\/a><\/p>\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>FDA Approves First Mesenchymal Stromal Cell Therapy to Treat Steroid-refractory Acute Graft-versus-host Disease The FDA has approved Ryoncil (remestemcel-L), the [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":8057,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center 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