{"id":8015,"date":"2024-06-30T11:56:00","date_gmt":"2024-06-30T08:26:00","guid":{"rendered":"https:\/\/drboroumandp7.com\/lando-klefner-syndrome\/"},"modified":"2024-11-25T10:40:16","modified_gmt":"2024-11-25T07:10:16","slug":"lando-klefner-syndrome","status":"publish","type":"post","link":"https:\/\/drboroumandp7.com\/en\/lando-klefner-syndrome\/","title":{"rendered":"Lando-Klefner syndrome<br>"},"content":{"rendered":"\n<div id=\"ez-toc-container\" class=\"ez-toc-v2_0_82_2 ez-toc-wrap-right counter-hierarchy ez-toc-counter ez-toc-grey ez-toc-container-direction\">\n<div class=\"ez-toc-title-container\">\n<p class=\"ez-toc-title\" style=\"cursor:inherit\">\u0622\u0646\u0686\u0647 \u062f\u0631 \u0627\u06cc\u0646 \u0646\u0648\u0634\u062a\u0647 \u0645\u06cc \u062e\u0648\u0627\u0646\u06cc\u062f<\/p>\n<span class=\"ez-toc-title-toggle\"><a href=\"#\" class=\"ez-toc-pull-right ez-toc-btn ez-toc-btn-xs ez-toc-btn-default ez-toc-toggle\" aria-label=\"Toggle Table of Content\"><span class=\"ez-toc-js-icon-con\"><span class=\"\"><span class=\"eztoc-hide\" style=\"display:none;\">Toggle<\/span><span class=\"ez-toc-icon-toggle-span\"><svg style=\"fill: #999;color:#999\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" class=\"list-377408\" width=\"20px\" height=\"20px\" viewBox=\"0 0 24 24\" fill=\"none\"><path d=\"M6 6H4v2h2V6zm14 0H8v2h12V6zM4 11h2v2H4v-2zm16 0H8v2h12v-2zM4 16h2v2H4v-2zm16 0H8v2h12v-2z\" fill=\"currentColor\"><\/path><\/svg><svg style=\"fill: #999;color:#999\" class=\"arrow-unsorted-368013\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"10px\" height=\"10px\" viewBox=\"0 0 24 24\" version=\"1.2\" baseProfile=\"tiny\"><path d=\"M18.2 9.3l-6.2-6.3-6.2 6.3c-.2.2-.3.4-.3.7s.1.5.3.7c.2.2.4.3.7.3h11c.3 0 .5-.1.7-.3.2-.2.3-.5.3-.7s-.1-.5-.3-.7zM5.8 14.7l6.2 6.3 6.2-6.3c.2-.2.3-.5.3-.7s-.1-.5-.3-.7c-.2-.2-.4-.3-.7-.3h-11c-.3 0-.5.1-.7.3-.2.2-.3.5-.3.7s.1.5.3.7z\"\/><\/svg><\/span><\/span><\/span><\/a><\/span><\/div>\n<nav><ul class='ez-toc-list ez-toc-list-level-1 ' ><li class='ez-toc-page-1 ez-toc-heading-level-1'><a class=\"ez-toc-link ez-toc-heading-1\" href=\"https:\/\/drboroumandp7.com\/en\/lando-klefner-syndrome\/#What_is_Landau_Kleffner_syndrome_LKS\" >What is Landau Kleffner syndrome (LKS)?<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-1'><a class=\"ez-toc-link ez-toc-heading-2\" href=\"https:\/\/drboroumandp7.com\/en\/lando-klefner-syndrome\/#Caused_by_Lando-Klefner_syndrome\" >Caused by Lando-Klefner syndrome<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-1'><a class=\"ez-toc-link ez-toc-heading-3\" href=\"https:\/\/drboroumandp7.com\/en\/lando-klefner-syndrome\/#Symptoms_of_Lando_Kleffner_syndrome\" >Symptoms of Lando Kleffner syndrome<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-1'><a class=\"ez-toc-link ez-toc-heading-4\" href=\"https:\/\/drboroumandp7.com\/en\/lando-klefner-syndrome\/#Diagnosis_Lando-Klefner_syndrome\" >Diagnosis Lando-Klefner syndrome<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-1'><a class=\"ez-toc-link ez-toc-heading-5\" href=\"https:\/\/drboroumandp7.com\/en\/lando-klefner-syndrome\/#Lando_Klefner_syndrome_treatment\" >Lando Klefner syndrome treatment<\/a><ul class='ez-toc-list-level-2' ><li class='ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-6\" href=\"https:\/\/drboroumandp7.com\/en\/lando-klefner-syndrome\/#Taking_anticonvulsants\" >Taking anticonvulsants<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-7\" href=\"https:\/\/drboroumandp7.com\/en\/lando-klefner-syndrome\/#speech_therapy\" >speech therapy<\/a><\/li><li class='ez-toc-page-1 ez-toc-heading-level-2'><a class=\"ez-toc-link ez-toc-heading-8\" href=\"https:\/\/drboroumandp7.com\/en\/lando-klefner-syndrome\/#Cognitive_behavioral_therapy\" >Cognitive behavioral therapy<\/a><\/li><\/ul><\/li><\/ul><\/nav><\/div>\n<h1 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"What_is_Landau_Kleffner_syndrome_LKS\"><\/span>What is Landau Kleffner syndrome (LKS)?<br\/><span class=\"ez-toc-section-end\"><\/span><\/h1>\n\n<p>Landau Kleffner syndrome is a type of neurological disorder and seizures in children that can lead to muteness. This syndrome starts from the ages of 2 to 8 years. Speech disorders often occur suddenly, and the disease can affect both the child&#8217;s mental abilities and his speech. Children with LKS have abnormal brain activity during sleep, and many also experience seizures.   <\/p>\n\n<h1 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Caused_by_Lando-Klefner_syndrome\"><\/span>Caused by Lando-Klefner syndrome<br\/><span class=\"ez-toc-section-end\"><\/span><\/h1>\n\n<p>The cause of Landoklefner syndrome is the mutation of the gene called GRIN2A in children with this syndrome. This gene is responsible for producing proteins that send signals to nerve cells (neurons) in the brain. Disturbance in the transmission of these messages will lead to speech or understanding problems, as well as seizures. Family history of epilepsy or convulsions is not common in these children.<br\/>   <br\/>Lando-Kelfner syndrome is often mistaken for autism, especially when an EEG shows abnormal results. Most parents go to the doctor when their children become deaf or hard of hearing.<br\/> <\/p>\n\n<p>Researchers believe that these gene mutations cause the electrical signals in their brains to go wrong. These abnormal signals can cause symptoms of LKS. They are also studying whether there is a connection between LKS and the immune system. An autoimmune response in which the immune system attacks the body&#8217;s own cells may contribute to LKS.<br\/><br\/>   <\/p>\n\n<h1 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Symptoms_of_Lando_Kleffner_syndrome\"><\/span>Symptoms of Lando Kleffner syndrome<br\/><span class=\"ez-toc-section-end\"><\/span><\/h1>\n\n<p>A child with Landau Kleffner syndrome may have the following symptoms:<br\/><\/p>\n\n<p>unable to speak<br\/><br\/>She or He may have a seizure.<br\/>The probability of suffering from behavioral disorders (such as attention deficit hyperactivity disorder) is higher.<\/p>\n\n<h1 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Diagnosis_Lando-Klefner_syndrome\"><\/span>Diagnosis Lando-Klefner syndrome<br\/><span class=\"ez-toc-section-end\"><\/span><\/h1>\n\n<p>In the first step, the neurologist examines the child&#8217;s medical records and clinical examinations.<br\/>Electroencephalography (brain tape) is often abnormal in these children, especially during sleep.<br\/>Metabolic and genetic tests<br\/>MRI, which shows normal results<\/p>\n\n<h1 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Lando_Klefner_syndrome_treatment\"><\/span>Lando Klefner syndrome treatment<br\/><span class=\"ez-toc-section-end\"><\/span><\/h1>\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Taking_anticonvulsants\"><\/span>Taking anticonvulsants<br\/><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n<p>In some cases, taking anticonvulsants such as clonazepam, diazepam, and levothyroxine can help reduce the number and severity of seizures and improve symptoms.<br\/><\/p>\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"speech_therapy\"><\/span>speech therapy<br\/><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n<p>This method is performed with the aim of improving pronunciation and reducing the symptoms of the disease, through pronunciation exercises, speech exercises and breathing exercises.<\/p>\n\n<h2 class=\"wp-block-heading\"><span class=\"ez-toc-section\" id=\"Cognitive_behavioral_therapy\"><\/span>Cognitive behavioral therapy<br\/><span class=\"ez-toc-section-end\"><\/span><\/h2>\n\n<p> This method aims to improve behavior and social interaction, using various techniques such as problem analysis, self-control exercises and changing thinking patterns.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>What is Landau Kleffner syndrome (LKS)? Landau Kleffner syndrome is a type of neurological disorder and seizures in children that [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":7610,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[493],"tags":[504,505,503,502,511,507,509,506,510,501,508],"class_list":["post-8015","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-educational-articles","tag-cell-therapy","tag-dr-amirreza-boroumand","tag-gene-therapy","tag-genetics","tag-lando-klefner-syndrome","tag-neurologist","tag-neurologist-en","tag-neurology","tag-p7medicine-en","tag-person-centered-medicine","tag-stem-cells"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Lando-Klefner syndrome - \u062f\u06a9\u062a\u0631 \u0627\u0645\u06cc\u0631\u0631\u0636\u0627 \u0628\u0631\u0648\u0645\u0646\u062f- \u0645\u062a\u062e\u0635\u0635 \u0645\u063a\u0632 \u0648 \u0627\u0639\u0635\u0627\u0628<\/title>\n<meta name=\"description\" content=\"Lando Kleffner is a type of neurological disorder and seizures in children that can lead to muteness. 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